Induction of severe autoimmune disease in normal mice by simultaneous action of multiple immunostimulators.
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چکیده
منابع مشابه
Induction of severe autoimmune disease in normal mice by simultaneous action of multiple immunostimulators
Either of two immunostimulating factors (lpr, lipopolysaccharide) enhanced the pathogenic autoimmune responses of MRL/n mice, but the serologic and immunopathologic characteristics differed. In contrast, either factor acting alone, caused minimal immunopathology in normal mice, despite autoantibody induction. Combined immunostimulation, however, caused fatal glomerulonephritis in normal-backgro...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1985
ISSN: 0022-1007,1540-9538
DOI: 10.1084/jem.161.2.423